In 1955, the great blues harpist Little Walter released 'My Babe', which was written by Willie Dixon, bassist and blues songwriter extraordinaire. The song is based on old gospel songs but with lyrics changed to be about love and cheating.
The song reached #1 on the R&B charts and was a great success for Walter and Chess Records:
Since then it's become a blues standard and was has been covered by just about everyone, including:
Sonny Boy Williamson with The Animals
George Thorogood & The Destroyers feat. Charlie Musselwhite
Ike & Tina Turner
Columbus Short as Little Walter, from Cadillac Records